TIMed CENTER Center for Technological Innovation in Medicine
The TIMed Center focuses on the development of technological innovations - in a first step - by the combination of biomedical analysis (bioinformatics), diagnostics (microscopy and laboratory analysis) and simulation (education and training systems). As a result of further expansion, the areas of virtual surgery, endo- and exo-prosthetics (intelligent prosthetics, biomechanics and motion analysis) as well as biomedical drugs and suitable, future research areas are to be integrated in the medium to long term.
Identification of correlations and patterns in biomedical data, e.g.: Factors influencing dementia, prediction of blood glucose concentrations in diabetic patients, relationship between biomedicine and psychotherapy
Exploration of protein-protein interactions, e.g. cell proliferation, cell division, immune responses, tumors or allergies from mass spectrometry data and micro-patterning assays.
Image processing via bioinformatics for the automated analysis of cellular macro- and nanostructures, e.g.: Bioinformatics methods enable microscopic analysis of cartilage tissue in 3D in connection with regenerative medicine and tissue engineering.
Sensor technology for "feeling" prostheses and motion analysis and for automated activity measurements and logging for physiotherapy, and rehabilitation measures by combination of signal acquisition of movements and machine learning, pattern recognition and mobile applications.
Biomimetic for the production Structured polymer surfaces in the micro- to nanometer range that mimic the mechanical and chemical properties of biological systems. Future applications are used in prosthetics (bone substitutes, dental prostheses, implants) but also e.g. For wound care and drug targeting.
Production of organ-like carrier structures for medical research, e.g. 3D model system for blood vessels for the investigation of arteriosclerosis or analysis of the metabolism via the blood-brain barrier. The technical and personnel infrastructure in international cooperation (INTERREG project CAC-SuMeR) is being developed for lithographic structuring and bio molecular analysis on a manometer scale.
Development of high-resolution 3D fluorescence microscopy systems for biomedical diagnostics.
Determination of the current cell status with real-time analysis by high-resolution microscopy techniques.
Investigations of samples by means of confocal, fluorescence and spectroscopy, photoacoustic methods and industrial CT, surface characterization and manipulation using atomic force microscopy (AFM).
Development of hybrid, surgical simulators from artificial, anatomical structures, computer models and virtual reality (e.g. simulated imaging and tactile feedback) as an alternative to expensive, dangerous or even impossible real-world experiments to enter new territory both technologically and medically and to provide a realistic education.
Investigating the role of protein-protein interactions in the arrangement of dynamic molecular complexes that receive and process information from receptors on the cell surface after ligand binding.
Effect of secondary plant ingredients on medically relevant surface molecules of human cells are analyzed by means of novel biophysical measurement methods and bioinformatics.
Identification and characterization of herbal antidiabetic ingredients for the prevention and treatment of diabetes.